GLADIUS HEALTH

A Framework

What Responsible TRT Looks Like

The online TRT market has a well-documented problem with overprescribing. This page is not a sales pitch. It is a framework for evaluating any provider — including ours.

The Evaluation Comes Before Everything

Labs first. Prescription second. Any provider who skips the lab step is not practicing medicine — they are filling orders.

The evaluation should involve a board-certified physician, not an algorithm or a questionnaire with automated approval. The physician needs to review both your symptoms and your bloodwork, ask follow-up questions, and make a clinical judgment. That process cannot be completed in three minutes.

If approval arrives before a physician has reviewed anything, that is worth paying attention to.

One Lab Result Is Not Enough Context

Testosterone levels fluctuate. Time of day, recent stress, poor sleep, acute illness, and alcohol consumption can each affect a reading meaningfully. Morning levels are typically higher than afternoon levels. A man who slept four hours the night before his blood draw may show suppressed levels that do not reflect his baseline.

A single data point is a starting place, not a conclusion. Responsible evaluation accounts for this — either by contextualising the result carefully or by retesting under better conditions before moving forward.

The Prescription Is Not the Finish Line

What does follow-up look like? How are side effects monitored? What happens if your levels run consistently high? What is the protocol if haematocrit elevates to a range that increases cardiovascular risk?

A provider who cannot answer these questions clearly before you start is not offering supervised care. The ongoing relationship matters. Testosterone therapy is not a one-time transaction.

Ask any prospective provider: what does your monitoring schedule look like after the first prescription? If the answer is vague, that is the answer.

Red Flags Worth Knowing

These are not hypothetical edge cases. They are documented practices across a meaningful portion of the online TRT market.

  • No lab requirement before prescribing
  • Approval within minutes of completing an online questionnaire, before any physician has reviewed anything
  • No documented follow-up or monitoring protocol
  • Prescribing to men whose baseline levels fall within or above the normal range
  • No questions about fertility intentions before initiating treatment that suppresses natural sperm production
  • Pricing structures that incentivise prescribing volume over clinical appropriateness

What a Good Evaluation Asks About

A thorough evaluation covers more than a symptom checklist and a testosterone number. It should address:

  • Symptom presentation and duration — how long, how consistent, how significantly impacting daily function
  • Prior testosterone testing and any previous treatment
  • Fertility intentions — TRT is not appropriate for men actively trying to conceive without additional medical management
  • Existing cardiovascular conditions or risk factors
  • Current medications — several common drugs suppress testosterone and should be ruled out before attributing symptoms to hypogonadism
  • Lifestyle factors: sleep quality, body composition, alcohol consumption, training volume

If the evaluation did not cover most of these, it was not a full evaluation.

Want to see our documented standards?

We publish exactly what labs are evaluated, what thresholds inform a prescribing recommendation, and what we hold our partner providers to.

Read our clinical standards →

Ready to start the evaluation?

Our 3-minute assessment is reviewed by a board-certified physician. If TRT is not appropriate, you will be told that directly.

Take the 3-Minute Assessment

Free assessment. No commitment required.